| Position | Names | Term of Office |
| C.1 | Stephen Mattoon, Consul | 1856-1859 |
| C.2 | John Chandler, Consul | 1859-1862 |
| C.3 | Aaron J. Westervelt, Consul | 1862-1863 |
| C.4 | James M. Hood, Consul | 1865-1869 |
| C.5 | Frederick W. Partridge, Consul | 1869-1876 |
| C.6 | David B. Sickels, Consul | 1876-1880 |
| M.1 | John H. Halderman, Minister | 1880-1885 |
| M.2 | Jacob T. Child, Minister | 1885-1890 |
| M.3 | Sempronius H. Boyd, Minister | Oct 1890 – June 1892 |
| M.4 | John Barrett, Minister | Feb 1894 – Apr 1898 |
| M.5 | Hamilton King, Minister | Jan 1898 – Sep 1912 |
| M.6 | Fred W. Carpenter, Minister | Sep 1912 – Nov 1913 |
| M.7 | William H. Honeybrook | 1914-1916 |
| M.8 | George Pratt Ingersoll | 1917-1918 |
| M.9 | George W.P. Hunt | 1920-1921 |
| M.10 | Edward E. Brodie, Minister | Oct 1921 – May 1925 |
| M.11 | William W. Russell, Minister | 1925-1926 |
| M.12 | Harold O. Mckenzie | 1926-1929 |
| M.13 | David E. Kaufman, Minister | 1930-1933 |
| M.14 | James M. Baker, Minister | Aug 1933 – May 1936 |
| M.15 | Edwin L. Neville, Minister | May 1937 – May 1940 |
| M.16 | Hugh G. Grant | 1940-1941 |
| M.17 | Willys R. Peck | Sep 1941-Dec 1941 |
| M.18 | Charles W. Yost | 1946 |
| M.19 | Edwin F. Stanton, | Apr 1946 – Apr 1947 (Minister) |
| A.1 | Minister then Ambassador | Apr 1947 – 1953 (Ambassador) |
| A.2 | William J. Donovan, Ambassador | Aug 1953 - Aug 1954 |
| A.3 | John E. Peurifoy, Ambassador | Sep 1954 – Aug 1955 |
| A.4 | Max W. Bishop, Ambassador | Dec 1955 – Jan 1958 |
| A.5 | U. Alexis Johnson, Ambassador | Jan 1958 – Apr 1961 |
| A.6 | Kenneth T. Young, Ambassador | May 1961 – Aug 1963 |
| A.7 | Graham Martin, Ambassador | Nov 1963 – Sep 1967 |
| A.8 | Leonard Unger, Ambassador | Sep 1967 – Nov 1973 |
| A.9 | William R. Kintner, Ambassador | Nov 1973 – Mar 1975 |
| A.10 | Charles S. Whitehouse, Ambassador | May 1975 – June 1978 |
| A.11 | Morton I. Abramowitz, Ambassador | July 1978 – June 1981 |
| A.12 | John Gunther Dean, Ambassador | Oct 1981 – 1985 |
| A.13 | William A. Brown, Ambassador | June 1985 – Aug 1988 |
| A.14 | Daniel A. O’Donohue, Ambassador | Aug 1988 – Aug 1991 |
| A.15 | David F. Lambertson, Ambassador | Sep 1991 – Aug 1995 |
| A.16 | William H. Itoh, Ambassador | Feb 1996 – Jan 1999 |
| A.17 | Richard E. Hecklinger, Ambassador | Feb 1999 – Dec 2001 |
| A.18 | Darryl N. Johnson, Ambassador | Dec 2001 – Dec 2004 |
| A.19 | Ralph L. Boyce, Ambassador | Dec 2004 – Dec 2007 |
| A.20 | Eric G. John, Ambassador | January 2008 - present |
